myopericytomas
Myopericytoma (MPC - myopericytomas) is a generic denomination to describe tumors showing differentiation toward perivascular myoid cells /myopericytes.
It has been suggested that MPC forms a morphologic continuum with glomus tumor (GT), angioleiomyoma (ALM), solitary myofibroma (SMF) and infantile myofibromatosis.
Myopericytoma showed a wide range of growth patterns; concentric perivascular whorls, hemangiopericytomatous areas, glomangiopericytoma (GPC)-type vessels and leiomyomatous foci. Intravascular growth was also seen.
These four interrelated groups of tumors had in common GPC-type vasculature and intraluminal cellular proliferation.
Diffuse immunoreactivity for alpha-smooth muscle actin and less staining intensity of muscle-specific actin can be observed.
See also
benign myopericytoma
malignant myopericytoma
References
Ide F, Mishima K, Yamada H, Saito I, Horie N, Shimoyama T, Kusama K. Perivascular myoid tumors of the oral region: a clinicopathologic re-evaluation of 35 cases. J Oral Pathol Med. 2008 Jan;37(1):43-9. PMID: 18154577
Dray MS, McCarthy SW, Palmer AA, Bonar SF, Stalley PD, Marjoniemi V, Millar E, Scolyer RA. Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases. J Clin Pathol. 2006 Jan;59(1):67-73. PMID: 16394283
Granter SR, Badizadegan K, Fletcher CD. Myofibromatosis in adults, glomangiopericytoma, and myopericytoma: a spectrum of tumors showing perivascular myoid differentiation. Am J Surg Pathol. 1998 May;22(5):513-25. PMID: 9591720