Human pathology

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mitochondrial respiratory chain complex II

The succinate dehydrogenase consists of only four subunits, all nuclearly encoded, and is part of both the respiratory chain and the Krebs cycle.

Pathology

- encephalomyopathy
- optic atrophy
- tumor

References

- Rustin P, Rotig A. Inborn errors of complex II—unusual human mitochondrial diseases. Biochim Biophys Acta. 2002 Jan 17;1553(1-2):117-22. PMID: 11803021