Human pathology

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malignant myopericytoma

Epidemiology

- no sex predominance (12405913)
- median age 67 years (range 19-81 years) (12405913)
- neck, arm, thigh and foot(12405913)

Synopsis

- highly mitotic myoid-appearing ovoid-to-spindle cells showing at least focally striking perivascular orientation resembling that seen in benign myopericytoma
- fascicular +/-
- thin-walled branching vessels +/-

Immunochemistry

- positivity for smooth muscle actin
- +/- dot-like desmin positivity

Prognosis

- possible metastases (12405913)

References

- McMenamin ME, Fletcher CD. Malignant myopericytoma: expanding the spectrum of tumours with myopericytic differentiation. Histopathology. 2002 Nov;41(5):450-60. PMID: 12405913