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lymphoid follicles

Lymphoid follicle BCL2 immunostaining in adenoid Pulmonary follicular lymphoid hyperplasia CD20 immunostaining of pulmonary lymphoid follicles Lymphoid follicles in normal tonsil (bcl2) Lymphoid follicles in normal tonsil (CD20) Lymphoid follicles in normal tonsil (CD3) Lymphoid follicles in normal tonsil (H&E)

Types

- primary lymphoid follicle
- secondary lymphoid follicle

Components

- germinal center
- marginal zone

Lesions

- lymphoid follicular hyperplasia
- follicular fragmentation
- follicular regression
- follicular lysis
- progressive transformation of germinal centers (PTGC)

Localization

- vesicular lymphoid nodule
- bone marrow lymphoid nodule

References

- Jones D. Dismantling the germinal center: comparing the processes of transformation, regression, and fragmentation of the lymphoid follicle. Adv Anat Pathol. 2002 Mar;9(2):129-38. PMID: 11917166