Liposclerosing myxofibrous tumor (LSMFT) is a benign fibro-osseous lesion that is characterized by mixture of histologic elements including lipoma, fibroxanthoma, myxoma, ischemic ossification, and fibrous dysplasia (FD)-like features.
Etiology
activating Gs alpha (GNAS1) mutation at the Arg201 codon (14652823)
References
Gilkey FW. Liposclerosing myxofibrous tumor of bone. Hum Pathol. 1993 Nov;24(11):1264. PMID: 8244329