Juvenile polyps are hamartomatous polyps found primarily in infants and children.
Predisposition
juvenile polyposis (JP) (MIM.174900) (MADH4 and BMPR1A mutations)
Cowden syndrome (CS) (MIM.158350) (PTEN mutations)
Bannayan-Riley-Ruvalcaba syndrome (BRRS) (MIM.153480) (PTEN mutations)
neurofibromatosis type 1 (NF1) (15150783)
NB: Although solitary juvenile polyps are benign lesions, but when present in juvenile polyposis (JP), they may lead to gastrointestinal cancers.
References
Merg A, Howe JR. Genetic conditions associated with intestinal juvenile polyps. Am J Med Genet C Semin Med Genet. 2004 Aug 15;129(1):44-55. PMID: 15264272