Intraneural perineurioma is a rare peripheral nerve sheath tumor consisting of intraneural proliferation of neoplastic perineurial cells.
Synopsis
numerous whorls consisting of concentric layers of spindle cells encircling the nerve fibers
Imunochemistry
vimentin
epithelial membrane antigen
glucose transporter protein 1 + (GLUT1 +)
S-100 -
CD34 -
Ultrastructure
perineurial cell differentiation
Cytogenetics
45,XX,add(14)(p13),-22,add(22)(q11.2)
46,XX,add(2)(q11.2),add(3)(q12) (16096405)
References
Brock JE, Perez-Atayde AR, Kozakewich HP, Richkind KE, Fletcher JA, Vargas SO. Cytogenetic aberrations in perineurioma: variation with subtype. Am J Surg Pathol. 2005 Sep;29(9):1164-9. PMID: 16096405