Human pathology

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gatekeeper tumour suppressor genes

Gatekeeper tumor suppresor genes directly regulate proliferation.

References

- Ehrhart JC, Gosselet FP, Culerrier RM, Sarasin A. UVB-induced mutations in human key gatekeeper genes governing signalling pathways and consequences for skin tumourigenesis. Photochem Photobiol Sci. 2003 Aug;2(8):825-34. PMID: 14521217