Human pathology

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familial schwannomatosis

Synopsis

- multiple schwannomas
- no vestibular schwannomas (as in neurofibromatosis type 2, NF2)

Etiology

- germline mutation of INI1/SMARCB1 (17357086)

References

- Hulsebos TJ, Plomp AS, Wolterman RA, Robanus-Maandag EC, Baas F, Wesseling P. Germline mutation of INI1/SMARCB1 in familial schwannomatosis. Am J Hum Genet. 2007 Apr;80(4):805-10. PMID: 17357086