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aspartic proteases

Memebers

integral membrane proteins

presenilins
signal peptide peptidase

pepsin
renin
cathepsin-D

References

Martoglio B, Golde TE. Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R201-6. Epub 2003 Sep 09. PMID: 12966028

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