antibody conjugates
Immunotherapeutics represent the largest group of molecules currently in development as new drug entities.
These versatile molecules are being investigated for the treatment of a range of pathological conditions including cancer, infectious and inflammatory diseases.
Antibodies can be used to exert biological effects themselves or as delivery agents of conjugated drug molecules.
Site-specific delivery of therapeutic agents has been an ultimate goal of the pharmaceutical industry in order to maximize drug action and minimize side effects.
References
McCarron PA, Olwill SA, Marouf WM, Buick RJ, Walker B, Scott CJ. Antibody conjugates and therapeutic strategies. Mol Interv. 2005 Dec;5(6):368-80. PMID: 16394252