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Home > G. Tumoral pathology > adenomatoid tumors

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adenomatoid tumors

Adenomatoid tumor is a benign, relatively rare neoplasm occurring primarily in the genital tract of both genders.

Localization

- adenomatoid tumor of the epididymis
- adenomatoid tumor of the tunica albuginea
- adenomatoid tumor of the testicle
- adenomatoid tumor of the ovary
- adenomatoid tumor of the myometrium
- adenomatoid tumor of the fallopian tube
- adenomatoid tumor of the parafallopian region
- adenomatoid tumor of the mediastinum (14707875)
- adenomatoid tumor of the adrenal gland (14506647)

Synopsis

- cystic spaces lined by flattened or cuboidal epithelial cells
- walls of the cysts: proliferation of small canalicular structures lined by round to polygonal epithelioid cells with vacuolated eosinophilic cytoplasm
- +/- infarction (14707867)
- fibrous tissue
- numerous slit-like and pseudotubular spaces
- thread-like bridging strands crossing the pseudotubular spaces (14571427)

Immunohistochemistry

- AE1/AE3 cytokeratin+
- CK5/CK6 cytokeratin+
- calretinin+
- CK7-
- CK20-
- alpha-fetoprotein-
- CD31-
- carcinoembryonic antigen-
- MOC-31-
- chromogranin-

Electron microscopy

- numerous long microvilli on the cell surface and abundant tonofilaments/desmosomal plaques in the tumor cells, characteristic of mesothelial cells

Keywords