Waldenstrom macroglobulinemia
Waldenstrom macroglobulinemia (WM) is a clinicopathologic syndrome in which a B-cell neoplasm involving the bone marrow, usually lymphoplasmacytic lymphoma (LPL), is associated with immunoglobulin M paraprotein in the serum.
Etiology
lymphoplasmacytic lymphoma
lymphoplasmacytoid lymphoma
small lymphocytic lymphoma/chronic lymphocytic leukemia
mantle cell lymphoma
follicular lymphoma
References
Lin P, Bueso-Ramos C, Wilson CS, Mansoor A, Medeiros LJ. Waldenstrom macroglobulinemia involving extramedullary sites: morphologic and immunophenotypic findings in 44 patients. Am J Surg Pathol. 2003 Aug;27(8):1104-13. PMID: 12883242