Human pathology

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TNC

MIM.187380 9q33

tenascin, tenacin

The tenacin family consist of large multimeric proteins involved in morphogenesis and cell adhesion.

Use in pathology

- Differential diagnosis of dermatofibroma (fibrous histiocytoma) vs dermatofibrosarcoma protuberans (11172295)

- DF DFSP
CD34 25% 80%
FXIIIa 95% 15%
Tenascin in the tumor 80% 80%
Tenascin at the dermal-epidermal junction 100% 0%

See also

- tenascins (TNs)