SLCA7
MIM.603593 14q11.2
cationic amino acid trasporter, y+ system
The SLC7A7 gene encodes the light subunit of a cationic amino acid transporter. Together with the heavy chain, 4F2hc (SLC3A2) (MIM.158070), the SLC7A7 protein forms a functional heterodimeric transporter on the basolateral cell membrane of epithelial cells that transfers lysine, arginine, and ornithine from the cell to the extracellular space.
Pathology
lysinuric protein intolerance (LPI) (MIM.222700)
See also
SLC7s