NTRK3
TrkC
TrkC is a member of the Trk family of tyrosine kinase receptors and plays an important role in the development and maintenance of neural tissues.
Pathology
ETV6-NTRK3 fusion gene by translocation t(12;15)(p13;q25)
- congenital fibrosarcoma (9462753)
- mesoblastic nephroma (9811336, 9823307)
- chronic myeloid leukemia
- secretory breast carcinoma (15101049)
References
Hisaoka M, Sheng WQ, Tanaka A, Hashimoto H. Gene expression of TrkC (NTRK3) in human soft tissue tumours. J Pathol. 2002 Aug;197(5):661-7. PMID: 12210087