REN(KCTD11) is a novel Hedgehog antagonist.
Pathology
Chromosome 17p deletion in medulloblastoma
References
Ferretti E, Smaele ED, Marcotullio LD, Screpanti I, Gulino A. Hedgehog checkpoints in medulloblastoma: the chromosome 17p deletion paradigm. Trends Mol Med. 2005 Dec;11(12):537-45. PMID: 16290230