Definition: Ischemia is a loss of blood supply from impeded arterial flow or reduced venous drainage in a tissue. Ischemia compromises the supply not only of oxygen, but also of metabolic substrates, including glucose (normally provided by flowing blood).
Localization
cerebral ischemia
limbs ischemia
myocardic ischemia
visceral ischemia
- hepatic ischemia
- renal ischemia
- digestive ischemia
See also
ischemic necrosis
References
Liang D, Dawson TM, Dawson VL. What have genetically engineered mice taught us about ischemic injury? Curr Mol Med. 2004 Mar;4(2):207-25. PMID: 15032714
Salvemini D, Cuzzocrea S: Superoxide, superoxide dismutase and ischemic injury. Curr Opin Investig Drugs 3:886, 2002.
Sheridan AM, Bonventre JV: Cell biology and molecular mechanisms of injury in ischemic acute renal failure. Curr Opin Nephral Hypertens 9:427, 2000.