Hedgehog-signaling related diseases
Classification
holoprosencephaly (SHH, PTCH)
Pallister-Hall syndrome (GLI3)
Grieg cephalopolysyndactyly (GLI3)
post-axial polydactyly type 3 (GLI3)
VACTERL (GLI2 and GLI3)
Rubinstein-Taybi syndrome
nevoid basal cell carcinoma syndrome (PTCH)
sporadic basal cell carcinoma (PTCH)
sporadic basal cell carcinoma (SMO)
sporadic medulloblastoma (PTCH)
Smith-Lemli-Opitz disease (DHCR7)
glioblastoma (GLI1)
References
Pasca di Magliano M, Hebrok M. Hedgehog signalling in cancer formation and maintenance.Nat Rev Cancer. 2003 Dec;3(12):903-11. PMID: 14737121
Bale AE, Yu KP. The hedgehog pathway and basal cell carcinomas. Hum Mol Genet. 2001 Apr;10(7):757-62. PMID: 11257109