FGFs
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Fibroblast growth factors
Fibroblast growth factors (FGFs) comprise a family of related polypeptides with broad mitogenic and cell survival activities.
Members
| FGF1 | FGF2 | FGF3 | FGF4 | FGF5 | FGF6 | FGF7 | FGF8 | FGF9 | FGF10 |
| FGF11 | FGF12 | FGF13 | FGF14 | FGF15 | FGF16 | FGF17 | FGF18 | FGF19 | FGF20 |
| FGF21 | FGF22 | FGF23 |
Pathology
| FGF3 | - | MIM.602115 | - | inner ear agenesis, microtia, and microdontia |
| FGF10 | 5p13-p12 | MIM.602115 | lacrimal gland aplasia | |
| FGF10 | 5p13-p12 | MIM.602115 | salivary gland aplasia | |
| FGF13 | Xq26.3 | MIM.300070 | ||
| FGF14 | 13q34 | MIM.601515 | autosomal dominant cerebellar ataxia | |
| FGF23 | 12p13.3 | MIM.605380 | autosomal dominant hypophosphatemic rickets | MIM.193100 |
References
Javerzat S, Auguste P, Bikfalvi A. The role of fibroblast growth factors in vascular development. Trends Mol Med. 2002 Oct;8(10):483-9. PMID: 12383771