ERG
MIM.165080 21q22.3
ERG1, ERG2, v-ets avian erythroblastosis virus E26 oncogene related
21q22.3
ERG has been associated with different fusion partners: FUS, EWSR1, ELF4.
Fusion genes
- ES/PNET tumors (Ewing sarcoma and pPNET)
ERG/FUS fusion gene by t(16;21)(p11;q22) (16p11 and 21q22) in
- de novo acute non lymphocytic leukemia (ANLL)
- ES/PNET tumors (Ewing sarcoma and pPNET)
ELF4/ERG fusion gene in acute myeloid leukemia (16303180)
Cytogenetics
t(X;21)(q25-26;q22)
References
Moore SD, Offor O, Ferry JA, Amrein PC, Morton CC, Dal Cin P. ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22). Leuk Res. 2006 Aug;30(8):1037-42. PMID: 16303180
MIM.165080