Human pathology

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Cajal cells

interstitial cells of Cajal

Lesions

- loss of interstitial cells of Cajal

- structural anomalies

Pathology

- paraneoplastic dysmotility
- Hirschsprung disease
- hypertrophic pyloric stenosis
- chronic intestinal pseudo-obstruction
- slow transit constipation

References

- Jain D, Moussa K, Tandon M, Culpepper-Morgan J, Proctor DD. Role of interstitial cells of Cajal in motility disorders of the bowel. Am J Gastroenterol. 2003 Mar;98(3):618-24. PMID: 12650797

- Pardi DS, Miller SM, Miller DL, Burgart LJ, Szurszewski JH, Lennon VA, Farrugia G. Paraneoplastic dysmotility: loss of interstitial cells of Cajal. Am J Gastroenterol. 2002 Jul;97(7):1828-33. PMID: 12135044

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