Human pathology

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CST3

MIM.604312 20p11.2

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Prion (a), cystatin C (b), transthyretin (TTR) amd amyloid fibril (...)
cystatin C, cystatin-C

Cystatin C belongs to the type II cystatin gene family. It is the most abundant extracellular inhibitor of cysteine proteases.

It is a 13-kD protein constitutively secreted shortly after its synthesis.

Pathology

- amyloidosis type 6 (icelandic type cerebroarterial amyloidosis or amyloidosis VI) (MIM.105150)