-->

| PubMed | eMedicine | OMIM | Google | Google images | Yahoo images | YouTube |

  • Printer friendly version

CDK5RAP2

MIM.608201 9q33.3

Pathology

- germline mutations in primary autosomal recessive microcephaly type 3 (MIM.604804)

- CDK5RAP2/PDGFRA fusion gene by ins(9;4)(q33;q12q25) in chronic eosinophilic leukemia (16845659)

References

- Walz C, Curtis C, Schnittger S, Schultheis B, Metzgeroth G, Schoch C, Lengfelder E, Erben P, Muller MC, Haferlach T, Hochhaus A, Hehlmann R, Cross NC, Reiter A. Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene. Genes Chromosomes Cancer. 2006 Oct;45(10):950-6. PMID: 16845659

- Bond, J.; Roberts, E.; Springell, K.; Lizarraga, S.; Scott, S.; Higgins, J.; Hampshire, D. J.; Morrison, E. E.; Leal, G. F.; Silva, E. O.; Costa, S. M. R.; Baralle, D.; Raponi, M.; Karbani, G.; Rashid, Y.; Jafri, H.; Bennett, C.; Corry, P.; Walsh, C. A.; Woods, C. G. : A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. Nature Genet. 37: 353-355, 2005. PMID : 15793586

- Moynihan, L.; Jackson, A. P.; Roberts, E.; Karbani, G.; Lewis, I.; Corry, P.; Turner, G.; Mueller, R. F.; Lench, N. J.; Woods, C. G. : A third novel locus for primary autosomal recessive microcephaly maps to chromosome 9q34. Am. J. Hum. Genet. 66: 724-727, 2000. PMID : 10677332