Human pathology

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CDAGS syndrome

Autosomal recessive condition that brings together apparently opposing pathophysiologic and developmental processes, including accelerated suture closure and delayed ossification.

Synopsis

- craniosynostosis
- delayed closure of the fontanel
- cranial defects
- clavicular hypoplasia
- anal malformations
- genitourinary malformations
- skin eruption

References

- Mendoza-Londono R, Lammer E, Watson R, Harper J, Hatamochi A, Hatamochi-Hayashi S, Napierala D, Hermanns P, Collins S, Roa BB, Hedge MR, Wakui K, Nguyen D, Stockton DW, Lee B. Characterization of a New Syndrome That Associates Craniosynostosis, Delayed Fontanel Closure, Parietal Foramina, Imperforate Anus, and Skin Eruption: CDAGS. Am J Hum Genet. 2005 Jul;77(1):161-8. PMID: 15924278