CD1d-restricted T cells have a pathogenic role in atherosclerosis. It could be an association between the cellular machinery that loads CD1 molecules with glycolipids and several key proteins in lipid metabolism.
See also
CD1s
References
Major AS, Joyce S, Van Kaer L. Lipid metabolism, atherogenesis and CD1-restricted antigen presentation. Trends Mol Med. 2006 Jun;12(6):270-8. PMID: 16651026