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Home > A. Molecular pathology > AP1 complex

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AP1 complex

AP1 is not a single protein, but constitutes a group of related dimeric basic region-leucine zipper proteins that belong to the JUNs (MIM.165160), FOSs (MIM.164810), MAFs (MIM.177075), and ATFs (MIM.603148) subfamilies.

Activator protein-1 (AP-1) transcription factor complex

References

- Eferl R, Wagner EF. AP-1: a double-edged sword in tumorigenesis. Nat Rev Cancer. 2003 Nov;3(11):859-68. PMID: 14668816

- Young MR, Yang HS, Colburn NH. Promising molecular targets for cancer prevention: AP-1, NF-kappa B and Pdcd4. Trends Mol Med. 2003 Jan;9(1):36-41. PMID: 12524209

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