ADAMTSs are members of extracellular matrix protease family (metalloproteinases). ADAMTSs have disintegrin and thromobospondin type 1 motifs.
Members
ADAMTS1 | ADAMTS2 | ADAMTS3 | ADAMTS4 | ADAMTS5 | ADAMTS6 | ADAMTS7 | ADAMTS8 | ADAMTS9 | ADAMTS10 |
ADAMTS11 | ADAMTS12 | ADAMTS13 | ADAMTS14 | ADAMTS15 | ADAMTS16 | ADAMTS17 | ADAMTS18 | ADAMTS19 | ADAMTS20 |
Pathology
ADAMTS10 | germline mutations | autosomal recessive Weill-Marchesani syndrome | |
ADAMTS13 | germline mutations | familial thrombotic thrombocytopenic purpura | MIM.604134 |
ADAMTS13 | germline mutations | Schulman-Upshaw syndrome | MIM.276850 |