Human pathology

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t(5;8)(p13;q12)

5p13 and 8q12

Genes involved

- PLAG1 at 8q12 and LIFR promoter at 5p13

References

- Voz ML, Astrom AK, Kas K, Mark J, Stenman G, Van de Ven WJ. The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter. Oncogene. 1998 Mar;16(11):1409-16. PMID: 9525740