Dysimmune diseases

• antisynthetase syndrome
  3 September 2021

  WKP
  Definition : Anti-synthetase syndrome is an autoimmune disease associated with interstitial lung disease , dermatomyositis , and polymyositis.
  Images
  https://twitter.com/leticiakawano/status/1433687136184774656
  See also
  autoimmune diseases

• histiocytic anomalies
  27 October 2020

  Examples
  histiocytoses
  Histiocytes containing non-digested bacteria (usually E. coli or Proteus sp.): Michaelis-Gutmann bodies
  See also
  histiocytes / macrophages

• mixed cryoglobulinemia
  9 February 2019

  Synopsis
  thrombi in small dermal vessels
  leukocytoclastic vasculitis
  Images
  Mixed cryoglobulinemia https://twitter.com/GeronimoJrLapac/status/929801815184629760
  Examples
  cotrimoxazole-associated mixed type 2 cryoglobulinemia
  See also
  vasculitis

• immunogenicity
  29 December 2018

  WKP
  Open references
  On the definition of a criterion of immunogenicity. Pradeu T, Carosella ED. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17858-61. PMID: #17101995# Free

• immune system evolution
  29 December 2018

  Paywall references
  Origins. On the origin of the immune system. Travis J. Science. 2009 May 1;324(5927):580-2. doi:10.1126/science.324_580. PMID: #19407173#
  Tracing the immune system’s evolutionary history. Travis J. Science. 1993 Jul 9;261(5118):164-5. PMID: #8327890#

• innate immune system
  20 August 2018

  WKP
  Definition: The innate immune system is one of the two main immunity strategies found in vertebrates (the other being the adaptive immune system). The innate immune system is an older evolutionary defense strategy, relatively speaking, and it is the dominant immune system response found in plants, fungi, insects, and primitive multicellular organisms.
  Components
  anatomical barriers
  inflammation
  complement system
  white blood cells / leulocytes mast cells phagocytes (...)

• Anti-Jo-1 antibodies
  17 June 2017

  Anti-Jo-1 antibody
  Anti-Jo-1 antibody is a myositis specific antibody commonly found in patients with idiopathic inflammatory myopathies.

• anti-SS-A(Ro) antibodies
  17 June 2017

  Anti-SS-A(Ro) antibodies are found in many autoimmune disorders, such as SLE, subacute cutaneous lupus, neonatal lupus, ANA negative lupus, Sjogren’s syndrome, primary biliary cirrhosis, chronic active hepatitis, and rheumatoid arthritis. Anti-SS-B (La) is far more specific for Sjogren’s syndrome than anti-SSA. It is also found in SLE.

• anti-centromere antibodies
  17 June 2017

  Systemic sclerosis, also known as scleroderma, has three subtypes: diffuse cutaneous, limited cutaneous (CREST) and overlap.
  Anti-centromere antibodies are associated with limited cutaneous systemic sclerosis (CREST).
  CREST is an acronym representing Calcinosis, Raynaud’s syndrome, Esophageal dysmotility, Sclerodactyly, and Telangiectasias.

• Systemic sclerosis
  17 June 2017

  scleroderma
  Systemic sclerosis, also known as scleroderma, has three subtypes: diffuse cutaneous, limited cutaneous (CREST) and overlap.
  Anti-centromere antibodies are associated with limited cutaneous systemic sclerosis (CREST).
  CREST is an acronym representing Calcinosis, Raynaud’s syndrome, Esophageal dysmotility, Sclerodactyly, and Telangiectasias.

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