Regional amplifications

• 13q32-34 amplification
  6 September 2007

  13q32-34 amplificon

• 4p15 amplification
  6 September 2007

  Tumors
  glioblastoma multiforme (#17002787#)
  Target gene
  SLA/LP (#17002787#)
  STIM2 (#17002787#)
  References
  Ruano Y, Mollejo M, Ribalta T, Fiano C, Camacho FI, Gomez E, de Lope AR, Hernandez-Moneo JL, Martinez P, Melendez B. Identification of novel candidate target genes in amplicons of Glioblastoma multiforme tumors detected by expression and CGH microarray profiling. Mol Cancer. 2006 Sep 26;5:39. PMID: (...)

• amp(7)(p12)
  6 September 2007

  7p12 amplicon, 7p12 amplification

• 18q amplification
  19 July 2007

  Subregions
  18q11.2 amplification
  Tumors
  rhabdomyosarcomas
  See also
  regional amplifications
  Oncobase

• 15q amplification
  19 July 2007

  Subregions
  15q12 amplification
  15q25-26 amplification
  Tumors
  rhabdomyosarcomas
  See also
  regional amplifications
  Oncobase

• 17q22-qter amplification
  19 July 2007

  Tumors
  rhabdomyosarcomas
  mammary carcinomas (breast cancer) (#18328948#)
  Target genes
  PPM1D (#18328948#)
  See also
  regional amplifications
  Oncobase
  References
  Pärssinen J, Alarmo EL, Karhu R, Kallioniemi A. PPM1D silencing by RNA interference inhibits proliferation and induces apoptosis in breast cancer cell lines with wild-type p53. Cancer Genet Cytogenet. 2008 Apr 1;182(1):33-9. PMID: (...)

• 9p21-23 amplification
  19 July 2007

  Tumors
  neuroblastomas
  See also
  regional amplifications
  Oncobase

• amp(2)(p24.1)
  19 July 2007

  2p24 amplification; 2p24 gain

• 11q22.2 amplification
  28 June 2007

  Tumors
  cervical squamous cell carcinoma
  Candidate genes
  Birc and MMP gene clusters
  See also
  11q22 amplification
  regional amplifications
  Oncobase
  References
  Narayan G, Bourdon V, Chaganti S, Arias-Pulido H, Nandula SV, Rao PH, Gissmann L, Durst M, Schneider A, Pothuri B, Mansukhani M, Basso K, Chaganti RS, Murty VV. Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: identification of candidate amplified and overexpressed genes. Genes Chromosomes (...)

• 3q24-28 amplification
  28 June 2007

  Tumors
  cervical squamous cell carcinoma (CSCC)
  References
  Narayan G, Bourdon V, Chaganti S, Arias-Pulido H, Nandula SV, Rao PH, Gissmann L, Durst M, Schneider A, Pothuri B, Mansukhani M, Basso K, Chaganti RS, Murty VV. Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: identification of candidate amplified and overexpressed genes. Genes Chromosomes Cancer. 2007 Apr;46(4):373-84. PMID: (...)

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