Prostate

• central zone gland
  18 March 2016

  central zone glands of the prostate
  Definition: The central zone (CZ) is located at the base of the prostate adjacent to the seminal vesicles. Its histology can be potential mimicker of high-grade prostatic intraepithelial neoplasia (PIN).
  See also
  prostatic central zone
  Images
  glands of central zone at the base of the prostate
  http://www.webpathology.com/image.asp?n=15&Case=19
  http://www.webpathology.com/image.asp?n=16&Case=19
  CZ histology is distinctive, as seen in (...)

• prostate carcinoma with neuroendocrine differentiation
  23 December 2014

  prostate cancer with neuroendocrine differentiation
  On July 31, 2013, the Prostate Cancer Foundation assembled a working committee on the molecular biology and pathologic classification of neuroendocrine (NE) differentiation in prostate cancer. New clinical and molecular data emerging from prostate cancers treated by contemporary androgen deprivation therapies, as well as primary lesions, have highlighted the need for refinement of diagnostic terminology to encompass the full spectrum of (...)

• discontinuous foci of cancer in prostatic biopsy
  2 December 2013

  References
  Discontinuous Foci of Cancer in a Single Core of Prostatic Biopsy: When it Occurs and Performance of Quantification Methods in a Private-practice Setting. Schultz L, Maluf CE, da Silva RC, Falashi Rde H, da Costa MV, Schultz MI. Am J Surg Pathol. 2013 Dec;37(12):1831-6. doi:10.1097/PAS.0000000000000112 .PMID: #24225844#

• prostatic hyperplasia
  6 June 2013

  prostate hyperplasia
  Types
  prostate adenomatous hyperplasia
  prostate basal cell hyperplasia
  See also
  prostatic anomalies

• microscopic mimics of prostatic carcinoma
  5 June 2013

  Benign Mimics of Prostate Cancer WebPathology
  Types
  partial atrophy of the prostate
  mucinous metaplasia
  atypical adenomatous hyperplasia
  Cowper glands
  post-atrophic hyperplasia (lobular atrophy)
  clear cell cribriform hyperplasia
  sclerosing adenosis
  prostatic xanthoma

• cervical adenocarcinoma in situ
  10 April 2013

  See also : cervical adenocarcinoma
  Images
  Adenocarcinoma in Situ of the Cervix, Pap and Biopsy Correlation by Ed Euthman
  Wikimedia : Endocervical adenocarcinoma in situ
  See also
  adenocarcinoma in situ

• Gleason score 6
  26 December 2012

  References
  Gleason score 6 adenocarcinoma: should it be labeled as cancer? Carter HB, Partin AW, Walsh PC, Trock BJ, Veltri RW, Nelson WG, Coffey DS, Singer EA, Epstein JI. J Clin Oncol. 2012 Dec 10;30(35):4294-6. PMID: #23032616#
  See also
  Gleason score 7

• high-grade PIN
  16 November 2012

  high grade PIN WPA
  Definition: High grade PIN is characterized by a more uniform morphologic alteration. High-grade PIN consists of intermediate to large size preexisting glands with proliferative changes resulting in hyperchromatic appearance.
  High grade PIN has atypical cells, and a basal cell layer. Cytologic features of HGPIN include prominent nucleoli and an increased nuclear size and N/C ratio. Low grade PIN has less prominent nucleoli. Architecturally it may be cribriform, (...)

• high grade prostatic adenocarcinoma
  27 September 2012

  Digital case
  JRC:14857 : high grade prostatic adenocarcinoma.

• perineural indentation by benign prostatic glands
  30 August 2012

  Perineural Indentation by Benign Prostatic Glands
  Benign prostatic glands may abut nerves. Occasionally, they may even partially or completely wrap around a nerve.
  This should not reflexly lead to the diagnosis of adenocarcinoma with perineural invasion. in this case, the gland lacks enlarged nuclei or nucleoli and shows scattered basal cells.
  Reference
  WebPathology: Perineural Indentation by Benign Prostatic (...)

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