Breast

• breast reduction mammaplasty
  22 August 2017

  Breast reduction mammaplasty (RMP)
  Breast reduction mammaplasty (RMP) for symptomatic macromastia or correction of asymmetry is performed in more than 100 000 patients per year in the United States.
  The reported incidence of significant pathologic findings (SPF), that is, carcinoma and atypical hyperplasia, ranges from 0.06% to 12.8%. No standard pathology assessment for RMP exists.
  Open references
  Recommendations for Pathologic Evaluation of Reduction Mammoplasty Specimens. 2017. (...)

• Toker cells
  20 August 2017

  Dr. Cyril Toker (1930-2015).
  Definition: Toker cells are epithelial cells with clear cytoplasm localized within the nipple epidermis.
  See also
  mammary anomalies mammary epithelial anomalies

• mammary myofibroblastoma
  14 June 2017

  Images
  mammary myofibroblastoma https://twitter.com/AJPerricone/status/874623969252474882
  See also
  mammary tumors
  myofibroblastoma
  mammary-type myofibroblastoma

• terminal lactiferous ducts
  30 May 2017

  TLDs
  |WKP|
  See also
  breast

• hormonoresistance in breast cancer
  27 May 2017

  Endocrine therapy is the mainstay of treatment of estrogen-receptor-positive (ER+) breast cancer with an overall survival benefit. However, some adaptive mechanisms in the tumor emerge leading to the development of a resistance to this therapy.
  Mechanisms of resistance to hormone therapy / hormonoresistance result in activation of transduction signal pathways, including the cell cycle regulation with cyclin D/CDK4/6/Rb pathway.
  The strategy of combined hormone therapy with targeted agents (...)

• mammary mucocele-like lesions
  16 May 2017

  MucoceleLike Lesion of the breast
  Mucocele-like lesions (MLLs) of the breast are characterized by cystic architecture with stromal mucin and frequent atypia, but it is unknown whether they convey long-term breast cancer risk.
  Images
  Mucocele-Like Lesion of the breast with atypia(ADH/FEA) https://twitter.com/VandaTorousMD/status/863919866566365185
  MLL is an uncommon breast lesion that is often associated with coexisting atypical hyperplasia (AH). However, in women older than 45 years, (...)

• columnar cell anomalies
  12 May 2017

  columnar cell lesions
  Examples
  columnar cell hyperplasia

• mammary sampling
  10 May 2017

  sampling of the breast
  Types
  FNA fine needle aspiration
  core biopsy
  surgical samples local excision / lumpectomy mastectomy
  See also
  sampling
  breast mammary anomalies mammary diseases mammary tumors

• adenomyoepithelial adenosis
  2 May 2017

  apocrine adenosis; secretory adenosis PO
  Definition: Uncommon variant of adenosis with proliferation of epithelial and myoepithelial cells. Adenomyoepithelial adenosis has prominent myoepithelial cells in 1-3 layers
  Myoepithelial cells are widely present in the breast, and their hyperplasia may result in a spectrum of disease ranging from myoepitheliosis to myoepithelial carcinoma.
  Images https://www.flickr.com/photos/jian-hua_qiao_md/26514276754
  Although considered benign, (...)

• nodular adenosis
  17 April 2017

  Nodular adenosis is a mammary adenosis presenting, as a mass (as nodular adenosis or adenosis tumor ) or as calcifications on imaging.
  Sclerosing adenosis is a form of adenosis in which there is an expansion of terminal duct lobular units (TDLU) due to proliferation of glandular components, accompanied by stromal proliferation which is usually dense and hyalinized with resultant compression and distortion of glands.
  Though it is often found as a microscopic lesion accompanying fibrocystic (...)

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