Breast

• cribriform DCIS
  1 December 2016

  Differential diagnosis
  mammary cribriform anomalies
  See also
  DCIS ductal carcinoma in situ

• mammary invasive papillary carcinoma
  1 December 2016

  mammary invasive cribriform carcinoma PO
  Images
  Invasive papillary ca commonly has a well-circumscribed pushing tumor front; look for areas that are more irregular. https://twitter.com/brstpathology/status/758688233156927488
  See also
  mammary cribriforma anomalies

• mammary nodular fasciitis
  18 November 2016

  nodular fasciitis of the breast
  See also : mammary spindle cell tumors
  See also
  nodular fasciitis
  Open references
  Nodular Fasciitis of the Breast.
  Moghimi M, Yazdian Anari P, Vaghefi M, Meidany A, Salehi H.
  Iran J Radiol. 2016 Jan 30;13(1):e18774. doi:10.5812/iranjradiol.18774.
  PMID: #27127573# Free

• mammary small glandular proliferations
  6 November 2016

  Small Glandular Proliferations of the Breast
  Types
  mammary sclerosing lesions / mammary slcerozing anomalies sclerosing adenosis radial scar mammary tubular carcinoma epithelial displacement after needle core biopsy low-grade adenosquamous carcinoma microglandular adenosis syringomatous adenoma
  See also
  mammary anomalies / mammary lesions

• PIK3CA-mutated mammary carcinoma
  1 November 2016

  PIK3CA-mutated mammary carcinoma
  PIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2-targeted therapies in breast cancer. (#25559818#)
  PIK3CA mutations were identified in 23% of HER2-positive breast tumors, and these mutations were associated with poorer outcome in all of the treatment arms. (#25559818#)
  Activating mutations in PIK3CA predicted poor pathologic complete response (pCR) in patients with HER2-positive breast (...)

• prosigna test
  17 October 2016

  Links
  http://prosigna.com/ http://www.nanostring.com/
  Open references
  The effects of lymph node status on predicting outcome in ER+ /HER2- tamoxifen treated breast cancer patients using gene signatures. Cockburn JG, Hallett RM, Gillgrass AE, Dias KN, Whelan T, Levine MN, Hassell JA, Bane A. BMC Cancer. 2016 Jul 28;16:555. doi:10.1186/s12885-016-2501-0.
  PMID: #27469239# Free
  Retrospective analysis of molecular scores for the prediction of distant recurrence according to baseline (...)

• mammary epithelial anomalies
  29 September 2016

  epithelial lesions of the breast; mammary lesions
  Types
  ductal anomalies / intraductal anomalies
  intraductal proliferative anomalies
  intraductal papillary anomalies
  other benign epithelial proliferations
  mammary adenosis
  sclerosing adenosis
  apocrine adenosis
  blunt duct adenosis
  microglandular adenosis
  adenomyoepithelial adenosis
  radial scar / complex sclerosing anomaly
  mammary adenomas
  tubular adenoma
  lactating adenoma
  apocrine adenoma
  pleomorphic adenoma (...)

• mammary cribriform anomalies
  29 September 2016

  cribriform lesions of the breast
  Types
  invasive cribriform carcinoma
  cribriform DCIS
  adenoid cystic carcinoma
  coll sphreulosis
  See also
  mammary anomalies
  cribriform anomalies

• sentinel lymph node micrometastasis in breast cancer
  29 September 2016

  References
  The significance of sentinel lymph node micrometastasis in breast cancer: Comparing outcomes with and without axillary clearance. 2016
  http://dx.doi.org/10.1016/j.breast.2016.09.005
  http://www.thebreastonline.com/article/S0960-9776(16)30166-7/fulltext?rss=yes

• terminal duct lobular units
  27 September 2016

  TDLU; terminal duct lobular unit; TDLUs
  Definition: The adult gland forms a tree-like structure starting at the nipple and branching through the stroma to end in lobules. The lobules are the ultimate milk producing functional units of the breast.
  In the resting gland, the terminal lobules are referred to as the Terminal Ductal Lobular Unit (TDLU). TDLUs can be classified according to their complexity.
  The terminal ductal lobular units (TDLUs) are the functional units of the breast. The (...)

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