Congenital hypogonadotropic hypogonadism (CHH) causes pubertal failure and infertility in both women and men, due to partial or total secretory failure of the two pituitary gonadotropins lutropin (LH) and follitropin (FSH) during periods of physiological activation of the gonadotropic axis.
Men and women with CHH frequently seek treatment for infertility after hypogonadism therapy.
Some etiologies, such as autosomal dominant or X‑linked Kallmann syndrome, raise the question of hereditary (...)
Home > E. Pathology by systems > Reproductive system > Male genital system
Male genital system
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male congenital hypogonadotropic hypogonadism
20 October 2011 -
STXBP2
29 April 2011syntaxin binding protein 2; UNC18B, Hunc18b; Munc18-2; Munc 18-2
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spermatid
22 April 2011Definition: The spermatid is the haploid male gametid that results from division of secondary spermatocytes. As a result of meiosis, each spermatid contains only half of the genetic material present in the original primary spermatocyte.
Spermatids are connected together by cytoplasmic material and have superfluous cytoplasmic material around their nuclei.
When formed, early round spermatids must undergo further maturational events in order to develop into spermatozoa, a process termed (...) -
spermatocyte
22 April 2011Definition: A spermatocyte is a male gametocyte, derived from a spermatogonium (spermatogonia), which is in the developmental stage of spermatogenesis during which meiosis occurs. It is located in the seminiferous tubules of the testis.
Spermatogenesis
The spermatogenesis is the developmental process which leads to the production of male gametes, termed spermatozoa or sperm.
Spermatogonial stem cells divide by mitosis to form primary spermatocytes.
The primary spermatocyte is initially (...) -
spermatogonia
22 April 2011spermatogonium
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paratesticular Wolffian multicystic mass
10 September 2010Paratesticular multicystic mass of Wolffian origin
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paratesticular papillary cystadenoma
10 September 2010Papillary Cystadenomas are formed by one or several cystic cavities lined by an epithelium with multiple papillary proliferations.
Synopsis
+/- areas of cribriform glandular proliferations
The papillae are composed of a thin, connective tissue layer and are lined by cylindrical simple or pseudostratified epithelium.
Most of the proliferative cylindrical cells show numerous cilia in the apical cytoplasm, although some clear globular cells lacking cilia also are observed.
A (...) -
paratesticular embryonic remnants
10 September 2010The normal development of the male genital tract is the result of the differentiation of wolffian derivatives and the involution of müllerian derivatives.
Wolffian remnants and Mullerian remnants are frequently observed in autopsies of fetal and postnatal cases, and they sometimes persist in adult men.
In adults, these embryonic remnants usually are an incidental finding in surgical specimens and rarely undergo proliferative changes.
Their most frequent pathologic characteristic is the (...) -
paratesticular Wolffian cyst
10 September 2010Paratesticular mesonephric cysts
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paratesticular cysts
10 September 2010Examples
paratesticular Wolffian cysts
paratesticular Mullerian cysts
paratesticular epidermoid cysts
See also
paratesticular lesions
paratesticular tumors