Blood and immunity

• TdT+ T-lymphoblast
  24 July 2013

  TdT+ T-lymphoblastic cells; TdT+ T-lymphoblasts
  Pathology
  TdT+ T-lymphoblastic populations are increased in Castleman disease, in Castleman disease in association with follicular dendritic cell tumors, and in angioimmunoblastic T-cell lymphoma. (#23060347#)
  References
  TdT+ T-lymphoblastic populations are increased in Castleman disease, in Castleman disease in association with follicular dendritic cell tumors, and in angioimmunoblastic T-cell lymphoma. Ohgami RS, Zhao S, Ohgami JK, (...)

• transformation of Waldenstrom macroglobulinemia
  12 December 2012

  Lymphoplasmacytic lymphoma-Waldenstrom’s macroglobulinemia; lymphoplasmacytic lymphoma/Waldenström macroglobulinemia
  Open References
  Development of diffuse large B-cell lymphoma in a patient with Waldenström’s macroglobulinemia/lymphoplasmacytic lymphoma: clonal identity between two B-cell neoplasms. Shiseki M, Masuda A, Watanabe N, Fujii M, Kimura T, Yoshinaga K, Mori N, Teramura M, Motoji T. Hematol Rep. 2011 Aug 31;3(2):e10. PMID: #22184531# (Free)
  Diffuse large B-cell lymphoma (...)

• chronic eosinophilic leukemia
  11 December 2012

  Cytogenetics
  trisomy 8 (+8) (#10414507#)
  References
  The role of trisomy 8 in the pathogenesis of chronic eosinophilic leukemia. Ma SK, Kwong YL, Shek TW, Wan TS, Chow EY, Chan JC, Chan LC. Hum Pathol. 1999 Jul;30(7):864-8. PMID: #10414507#

• lymphoblastic transformation in chronic myeloid leukemia
  10 December 2012

  References
  MLPA is a powerful tool for detecting lymphoblastic transformation in chronic myeloid leukemia and revealing the clonal origin of relapse in pediatric acute lymphoblastic leukemia. Alpár D, de Jong D, Savola S, Yigittop H, Kajtár B, Kereskai L, Pajor L, Szuhai K. Cancer Genet. 2012 Sep;205(9):465-9. PMID: #22939399#

• plasmacytoid dendrtic cell tumors
  3 November 2012

  plasmacytoid dendrtic cell proliferations
  Reference
  CD4(+) CD56(+) lineage-negative malignancies are rare tumors of plasmacytoid dendritic cells. Reichard KK, Burks EJ, Foucar MK, Wilson CS, Viswanatha DS, Hozier JC, Larson RS. Am J Surg Pathol. 2005 Oct;29(10):1274-83. PMID: #16160468#

• myelomonocytic tumors
  3 November 2012

  Myelomonocytic proliferations
  Reference
  Specific Skin Lesions in Chronic Myelomonocytic Leukemia: A Spectrum of Myelomonocytic and Dendritic Cell Proliferations. A Study of 42 Cases. Vitte F, Fabiani B, Bénet C, Dalac S, Balme B, Delattre C, Vergier B, Beylot-Barry M, Vignon-Pennamen D, Ortonne N, Algros MP, Carlotti A, Samaleire D, Frouin E, Levy A, Laroche L, Theate I, Monnien F, Mugneret F, Petrella T. Am J Surg Pathol. 2012 Sep;36(9):1302-1316. PMID: (...)

• chronic myelomonocytic leukemia
  27 August 2012

  CMML; CMMOL
  Definition: Chronic myelomonocytic leukemia (CMML or CCMOL) is a rare clonal hematopoietic disorder.
  Cutaneous CMML tumors
  Chronic myelomonocytic leukemia (CMML) can also involve the skin.
  A minimal panel of immunohistochemical markers including CD68, CD1a, S100, Langerin, and CD123 is necessary to make the correct classification in this spectrum of cutaneous CMML tumors, in which dendritic cell lineage plays an important role.
  Reference
  Specific Skin Lesions in Chronic (...)

• blastic NK-cell malignant lymphoma
  18 June 2012

  Blastic natural killer cell malignant lymphoma

• X-linked lymphoproliferative syndrome type 2
  12 January 2012

  XLP2
  X-linked lymphoproliferative syndrome-2 (XLP2) is caused by mutation in the gene encoding the X-linked inhibitor of apoptosis (XIAP; MIM.300079).
  See also
  X-linked lymphoproliferative syndromes (XLPs) X-linked lymphoproliferative syndrome type 1 (XLP1) (MIM.308240) X-linked lymphoproliferative syndrome type 2 (XLP2)

• monomorphic B-cell PTLD
  1 January 2012

  References
  Gene expression profiling of Epstein-Barr virus-positive and -negative monomorphic B-cell posttransplant lymphoproliferative disorders. Craig FE, Johnson LR, Harvey SA, Nalesnik MA, Luo JH, Bhattacharya SD, Swerdlow SH. Diagn Mol Pathol. 2007 Sep;16(3):158-68. PMID: #17721324#

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