Blood and immunity

• Tregs
  5 October 2007

  CD4+CD25+ regulatory T cells, T(reg) cells, FOXP3+ regulatory T cells

• acute basophilic leukemia
  17 September 2007

  AGCOH
  Definition: Acute basophilic leukemia is rare type of acute myeloid leukemia.
  Synopsis
  Phenotype: cell stem origin basophilic precursor
  Epidemiology: very rare but might be prominent in infants
  Clinics: hyperhistaminemia syndrome
  Cytology
  major component of undifferentiated blasts
  minor component of basophilic blasts blasts containing large granules reacting positively to toluidine blue staining
  Variants
  Acute basophilic leukemia (ABL) can arise from chronic (...)

• essential thrombocythemia
  29 July 2007

  polycythemia vera

• erythroblastosis fetalis
  24 July 2007

  Localization
  hepatic erythroblastosis fetalis
  splenic erythroblastosis fetalis
  Videos
  Hepatic erythroblastosis fetalis by Washington Deceit

• imatinib-resistant chronic myeloid leukaemia
  3 July 2007

  References
  Weisberg E, Manley PW, Cowan-Jacob SW, Hochhaus A, Griffin JD. Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia. Nat Rev Cancer. 2007 May;7(5):345-56. PMID: #17457302#

• 8p11 myeloproliferative syndrome
  21 June 2007

  The 8p11 myeloproliferative syndrome (EMS) is a chronic myeloproliferative disorder molecularly characterized by fusion of various 5’ partner genes to the 3’ part of the fibroblast growth factor receptor 1 (FGFR1) gene at 8p11, resulting in constitutive activation of the tyrosine kinase activity contained within FGFR1.
  EMS is associated with a high risk of transformation to acute myeloid leukemia (AML), but the mechanisms underlying the disease progression are unknown.
  Cytogenetics (...)

• monoblastic leukemia
  1 May 2007

  Variants
  fetal monoblastic leukemia
  neonatal monoblastic leukemia
  See also
  Leukemias

• fetal histiocytoses
  1 May 2007

  The histiocytoses are a group of disorders of the monophagocytic system having a variety of clinical and pathological findings. They occur less often during the perinatal period than later in life.
  Types
  Langerhans cell histiocytosis (LCH) disseminated Langerhans cell histiocytosis (disseminated LCH)
  hemophagocytic lymphohistiocytoses (HLH)
  congenital juvenile xanthogranuloma (JXG)
  References
  Isaacs H Jr. Fetal and neonatal histiocytoses. Pediatr Blood Cancer. 2006 (...)

• hepatitis-associated aplastic anemia
  10 April 2007

  immune-mediated hepatitis-associated aplastic anemia (HAAA or HAA)

• acute myelomonocytic leukemia
  26 March 2007

  juvenile myelomonocytic leukaemia

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