Hepatic Capsular and Subcapsular Pathologic Conditions
Open references
https://pubs.rsna.org/doi/abs/10.1148/rg.285075089
Home > E. Pathology by systems > Digestive system > Liver and pancreatobiliary system > Liver
Liver
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hepatic capsular and subcapsular anomalies
3 November 2022 -
hepatic nodule
3 November 2022liver nodule
Exemples
hepatic fibrous nodule hepatic solitary fibrous tumor / primary solitary fibrous tumors of liver
hepatocytic nodule dysplastic liver nodule
See also
nodules / nodule
hepatic anomalies -
cyst of the hepatic capsule
26 September 2022cyst of the Glisson capsule
cyst of the Glisson capsule -
hepatic capsule
26 September 2022Glisson capsule
Pathology (examples)
cyst of the Glisson capsule
non-traumatic pseudocyst of Glisson capsule (#20096426#) cerebrospinal fluid pseudocysts in the peritoneal cavity following ventriculoperitoneal shunt
pseudolipoma of the Glisson capsule https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8582619/ -
macrotrabecular massive hepatocellular carcinoma
26 September 2022macrotrabecular-massive HCC PO
Definition : Subtype of hepatocellular carcinoma with macrotrabecular pattern (≥ 6 - 10 cells thick). Macrotrabecular pattern must represent more than 50% of the tumor.
Images
https://twitter.com/emma_furth/status/1574870532452864000
Synopsis
hepatocellular carcinoma
> 50% growth of macrotrabecular pattern (≥ 6 - 10 cells thick)
Trabeculae observed in cross sections are bordered by a complete rim of CD34 positive endothelial cells in more (...) -
intrahepatic cholangiocarcinoma
22 September 2022iCCA PO
Definition : Intrahepatic cholangiocarcinoma (iCCA) is a malignant intrahepatic epithelial neoplasm with biliary differentiation, arising in the liver periphery / proximal to the left and right hepatic ducts (WHO 2019)
Microscopical synopsis
iCCA consists of infiltrating well formed or cribriform glands in an abundant fibrous stroma (Liver Int 2019;39:7, Surg Pathol Clin 2018;11:403)
Malignant glands are lined by cells with varying degrees of atypia and pleomorphism (...) -
primary sclerosing cholangitis
17 September 2022PSC WKP PO
Types
neonatal sclerosing cholangitis
auto-immune sclerosing cholangitis
Microscopy synopsis
"onion skin" fibrosis around affected medium sized bile ducts; smaller ducts rarely affected (except in small duct primary sclerosing cholangitis), meaning biopsy sampling rarely demonstrates this finding
progressive atrophy of bile duct epithelium and obliteration of the lumen, leaving a fibrous scar
ductular reaction and cholestasis may (...) -
well-differentiated hepatocellular anomalies
7 September 2022Types
focal nodular hyperplasia (FNH) / FNH-like anomalies
hepatocellular adenoma
dysplastic nodules
well-differentiated hepatocellular carcinoma (HCC)
Differential diagnosis
Mimics PEComa ( perivascular epithelioid cell neoplasm ) well-differentiated neuroendocrine tumor , especially oncocytic variant
See also
hepatocellular anomalies -
hepatocellular anomalies
7 September 2022hepatocellular lesions
Appearance
well-differentiated hepatocellular anomalies
poorly-differentiated hepatocellular anomalies
undifferentiated hepatocellular anomalies -
alcoholic hepatitis
23 March 2022WKP
Definition : Alcoholic hepatitis is hepatitis (inflammation of the liver) due to excessive intake of alcohol.