Colon and rectum

tumor budding in colorectal adenocarcinoma
10 October 2016

tumor budding in colorectal cancer
Definition: Tumor budding is a well-established adverse prognostic factor in colorectal cancer.
Images
Recommendations for Reporting Tumor Budding in CRC based on the International Tumor Budding Consensus Conference 2016 at ESPIAP Cologne2016 https://twitter.com/pathologia/status/781235895932510209
By tumors
tumor budding in colorectal carcinoma (CRC) Tumor budding is a well-established adverse prognostic factor in colorectal cancer.
Open (...)
high-grade colorectal neuroendocrine tumor
19 September 2016

High-Grade Colorectal Neuroendocrine Tumors
High-Grade Colorectal Neuroendocrine Tumors
Therapy
BRAF-V600E Mutations in High-Grade Colorectal Neuroendocrine Tumors May Predict Responsiveness to BRAF-MEK Combination Therapy. (#27048246#)
high-grade neuroendocrine carcinoma arising from a colorectal adenoma
3 September 2016

Primary high-grade neuroendocrine carcinoma emerging from an adenomatous polyp
References
Primary high-grade neuroendocrine carcinoma emerging from an adenomatous polyp in the setting of familial adenomatous polyposis. Detweiler CJ, Cardona DM, Hsu DS, McCall SJ. BMJ Case Rep. 2016 Feb 16;2016. doi:10.1136/bcr-2015-214206.
PMID: #26884076#
colorectal neuroendocrine tumors
3 September 2016

Neuroendocrine Tumors of the Large Intestine / of the colon PO
low-grade colorectal neuroendocrine tumors
high-grade colorectal neuroendocrine tumors colorectal neuroendocrine carcinoma
Open references
Neuroendocrine Tumors of the Large Intestine: Clinicopathological Features and Predictive Factors of Lymph Node Metastasis.
Kojima M, Ikeda K, Saito N, Sakuyama N, Koushi K, Kawano S, Watanabe T, Sugihara K, Ito M, Ochiai A.
Front Oncol. 2016 Jul 18;6:173. doi: (...)
intestinal low-grade tubuloglandular adenocarcinoma
24 August 2016

References
Intestinal low-grade tubuloglandular adenocarcinoma in inflammatory bowel disease. Levi GS, Harpaz N. Am J Surg Pathol. 2006 Aug;30(8):1022-9. PMID: #16861975#
intramucosal poorly differentiated colorectal carcinoma
24 August 2016

References
Intramucosal poorly differentiated colorectal carcinoma: can it be managed conservatively?
Shia J, Klimstra DS.
Am J Surg Pathol. 2008 Oct;32(10):1586-8; author reply 1588-9.
doi:10.1097/PAS.0b013e31817ec2cd.
PMID: #18724239#
Poorly differentiated colorectal carcinoma with invasion restricted to lamina propria (intramucosal carcinoma): a follow-up study of 15 cases. Lewin MR, Fenton H, Burkart AL, Sheridan T, Abu-Alfa AK, Montgomery EA. Am J Surg Pathol. 2007 (...)
colorectal poorly differentiated neuroendocrine carcinoma
24 August 2016

References
Colorectal poorly differentiated neuroendocrine carcinomas and mixed adenoneuroendocrine carcinomas: insights into the diagnostic immunophenotype, assessment of methylation profile, and search for prognostic markers. La Rosa S, Marando A, Furlan D, Sahnane N, Capella C. Am J Surg Pathol. 2012 Apr;36(4):601-11. doi:10.1097/PAS.0b013e318242e21c.
PMID: #22314183#
grading of colorectal adenocarcinoma
24 August 2016

References
Interlaboratory Variability in the Histologic Grading of Colorectal Adenocarcinomas in a Nationwide Cohort. Kuijpers CC, Sluijter CE, von der Thüsen JH, Grünberg K, van Oijen MG, van Diest PJ, Jiwa M, Nagtegaal ID, Overbeek LI, Willems SM. Am J Surg Pathol. 2016 Aug;40(8):1100-8. doi:10.1097/PAS.0000000000000636.
PMID: #26975039#
Site-specific tumor grading system in colorectal cancer: multicenter pathologic review of the value of quantifying poorly differentiated clusters. (...)
poorly differentiated colorectal adenocarcinoma
24 August 2016

PDCA
Open references
Poorly differentiated cecal adenocarcinoma showing prominent rhabdoid feature combined with appendiceal mucinous cystadenoma: A case report and review of the literature. Cho IJ, Kim SS, Min YD, Noh MW, Hong R. Oncol Lett. 2015 Apr;9(4):1527-1530. PMID: #25788994# (Free)
References
Loss of CDX2/CK20 expression is associated with poorly differentiated carcinoma, the CpG island methylator phenotype, and adverse prognosis in microsatellite-unstable colorectal (...)
colorectal medullary carcinoma
24 August 2016

undifferentiated carcinoma, solid type poorly differentiated carcinoma, large cell minimally differentiated carcinoma; Medullary-type poorly differentiated adenocarcinoma
PO
Definition: WHO recognized subtype of colon carcinoma with solid growth pattern (Hum Pathol 1999;30:843).
It is relatively rare; usually quoted as < 1% of colorectal neoplasms (Int J Oncol 2010;37:901). Often elderly women (average age 70 years). Usually right sided.
Strongly associated with high degree of (...)

0 | ... | 40 | 50 | 60 | 70 | 80 | 90 | 100 | 110 | 120 | ... | 380

E. Pathology by systems