Colon and rectum

• early colorectal adenocarcinoma
  6 January 2015

  early colorectal cancer
  See also
  colorectal adenocarcinoma
  Open references
  Endoscopic resection as unique treatment for early colorectal cancer. Revista Española de Enfermedades Digestivas. Rev. esp. enferm. dig. v.102 n.7 Madrid jul. 2010. http://dx.doi.org/10.4321/S1130-01082010000700006

• colorectal adenoma with adenocarcinoma
  6 January 2015

  colorectal polyps with invasive adenocarcinoma ; Cancerised Adenoma; Malignant colorectal polyps
  See also : colorectal adenoma
  Invasion in pediculated polyp
  See : Haggitt classification system
  Haggitt
  Haggitt defined the submucosal invasion in all sessile polyps as level 4 and therefore associated with bad outcome, independently of the affection or not of the resection margins.
  Despite Haggitt’s classification has been widely used to evaluate the resection quality of endoscopic (...)

• Colorectal cancer metastasis
  6 January 2015

  References
  Nordlinger B, Guiguet M, Vaillant J, et al. Surgical resection of colorectal carcinoma metastases to the liver: a prognostic scoring system to improve case selection, based on 1568 patients. Cancer. 1996;77:1254-1262
  Ueno H, Mochizuki H, Hatsuse K, et al. Indicators for treatment strategies of colorectal liver metastases. Ann Surg. 2000;231:59-66
  Minagawa M, Makuuchi M, Torzilli G, et al. Extension of the frontiers of surgical indications in the treatment of liver metastases (...)

• BRAF-V600E in colorectal cancer
  30 September 2014

  BRAFV600E in CRC; BRAFV600E in colorectal cancer
  Synopsis
  Excluding Lynch syndrome
  In colorectal carcinoma, the presence of the BRAFV600E mutation can be used to virtually exclude Lynch syndrome in mismatch repair-deficient tumors.
  Immunohistochemistry Facilitates Universal Screening of Colorectal Cancers for Lynch Syndrome. (#23797718#)
  BRAFV600E mutation in microsatellite-unstable (MSI) colorectal carcinomas (CRCs) virtually excludes Lynch syndrome (LS).
  Prognostic biomarker (...)

• colorectal cancer staging
  20 August 2014

  Colorectal cancer is the third most common malignancy in both men and women, and the second leading cause of cancer-related death in western developed countries.
  Currently, the tumor stage remains to be the most important determinant of prognosis in colorectal cancer and it is the basis for the authoritative patient management guidelines that influence most patient management decisions.
  The International Union Against Cancer (UICC)/American Joint Committee on Cancer (AJCC) TNM (...)

• tumoral deposits
  20 August 2014

  tumor deposits; tumoral deposit; Extramural Cancer Deposits Without Nodal Structures; tumoral deposit in colorectal cancer
  Definition: Cancer foci having no histologic evidence of lymph node structure.
  Tumor deposits: AJCC 8th Edition defintion :
  Tumor focus in the pericolic/perirectal fat or in adjacent mesentery within the Iymph drainage area of the primary tumor, but without identifiable Iymph node or vascular structure
  If vessel wall or its remnant identified (H&E, elastic, (...)

• mycophenolate-associated colitis
  14 October 2013

  Mycophenolate mofetil (MMF) is a T-cell inhibitor frequently used in the treatment of acute allograft rejection. MMF may cause colitis that clinically and histologically resembles graft-versus-host disease (GVHD).
  A variety of histologic features, in particular, eosinophils >15 per 10 HPF, lack of endocrine cell aggregates in the lamina propria, and lack of apoptotic microabscesses, can be used by pathologists to help separate MMF from GVHD-induced colitis in routine clinical practice. (...)

• serrated lesions
  22 September 2013

  serrated precursor lesion; serrated precursor lesions; Serrated lesions of the colorectum; sessile serrated lesions
  Serrated lesions of the colorectum are the precursors of perhaps one-third of colorectal cancers (CRCs).
  Serrated lesions should be classified pathologically according to the World Health Organization criteria as:
  hyperplastic polyp (PH),
  sessile serrated adenoma / polyp (SSA/P) with or without cytological dysplasia,
  traditional serrated adenoma (TSA) .
  SSA/P and TSA (...)

• colonic eosinophilic cryptitis
  24 July 2013

  See also
  colonic chronic cryptitis colonic lymphocytic cryptitis
  colonic cryptitis colonic acute cryptitis (colonic neutrophilic cryptitis)

• cord colitis syndrome
  15 July 2013

  Cord colitis syndrome (CCS) is a recently described diarrheal illness of uncertain pathogenesis that affects recipients of umbilical cord blood transplant and is associated with negative cultures.
  CCS exhibits a peculiar histopathologic appearance, as it commonly manifests as granulomatous inflammation involving the upper and lower gastrointestinal tract, with features of chronicity in the colon.
  Importantly, the treatment for CCS differs from that for acute graft-versus-host disease, (...)

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