TMPRSS2:ERG gene rearrangement was found to be highly specific for and detected in approximately 50% of prostate cancer.
The P63/ERG double immunostain combines the high sensitivity of P63 and the high specificity of ERG and may be potentially useful in the work-up of difficult prostate biopsies. (#21623182#)
The high specificity of ERG for the presence of cancer may have important implications for prostate biopsy interpretation and needs to be further validated in larger prospective (...)
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