Model organisms

• multicellularity
  18 January 2006

  Links
  Why Cancer Isn’t Going Anywhere. http://www.slate.com/articles/technology/future_tense/2017/04/cancer_has_been_with_us_since_the_origins_of_multicellularity.html
  References
  Martindale MQ. The evolution of metazoan axial properties. Nat Rev Genet. 2005 Dec;6(12):917-27. PMID: #16341072#
  Williams JG, Noegel AA, Eichinger L. Manifestations of multicellularity: Dictyostelium reports in. Trends Genet. 2005 Jul;21(7):392-8. PMID: (...)

• biological models of disease
  12 June 2005

  References
  Butcher EC. Innovation: Can cell systems biology rescue drug discovery? Nat Rev Drug Discov. 2005 Jun;4(6):461-7. PMID: #15915152#

• digital three-dimensional models of development
  4 October 2004

  Digital models of organs, cells and subcellular structures have become important tools in biological and medical research.
  Reaching far beyond their traditional widespread use as didactic tools, computer-generated models serve as electronic atlases to identify specific elements in complex patterns, and as analytical tools that reveal relationships between such pattern elements that would remain obscure in two-dimensional sections.
  Digital models also offer the unique opportunity to store (...)

• Drosophila melanogaster
  4 October 2004

  Videos
  Drosophila development
  Websites
  BDGP-Berkeley Drosophila Genome Project (The Berkeley Drosophila Genome Project (BDGP) is a consortium of the Drosophila Genome Center)
  References
  Wood W, Jacinto A. Drosophila melanogaster embryonic haemocytes: masters of multitasking. Nat Rev Mol Cell Biol. 2007 Jul;8(7):542-51. PMID: #17565363#
  Vidal M, Cagan RL. Drosophila models for cancer research. Curr Opin Genet Dev. 2006 Feb;16(1):10-6. PMID: #16359857#
  Brumby AM, Richardson HE. (...)

• Dictyostelium discoideum
  30 September 2004

  The social amoeba Dictyostelium discoideum is increasingly being used as a simple model for the investigation of problems that are relevant to human health:
  analysis of immune-cell disease and chemotaxis
  centrosomal abnormalities and lissencephaly
  bacterial intracellular pathogenesis
  mechanisms of neuroprotective and anti-cancer drug action
  A multicellular model
  Dictyostelium discoideum grow unicellularly, but develop as multicellular organisms. At two stages of development, their (...)

• cnidarians
  20 September 2004

  References
  Ball EE, Hayward DC, Saint R, Miller DJ. A simple plan—cnidarians and the origins of developmental mechanisms. Nat Rev Genet. 2004 Aug;5(8):567-77. PMID: #15266339#

• Yeasts
  16 August 2004

  References
  Boone C, Bussey H, Andrews BJ. Exploring genetic interactions and networks with yeast. Nat Rev Genet. 2007 Jun;8(6):437-49. PMID: #17510664#
  Simon JA, Bedalov A. Yeast as a model system for anticancer drug discovery. Nat Rev Cancer. 2004 Jun;4(6):481-92. PMID: #15170450#

• model organisms
  28 May 2004

  References
  Anderson KV, Ingham PW. The transformation of the model organism: a decade of developmental genetics. Nat Genet. 2003 Mar;33 Suppl:285-93. PMID: #12610538#
  Davis RH. The age of model organisms. Nat Rev Genet. 2004 Jan;5(1):69-76. PMID: #14708017#

• Tetrahymena thermophila
  23 November 2003

  References
  Turkewitz AP, Orias E, Kapler G. Functional genomics: the coming of age for Tetrahymena thermophila. Trends Genet. 2002 Jan;18(1):35-40. PMID: #11750699#

• Caenorhabditis elegans
  21 November 2003

  Livres
  Caenorhabditis Elegans : Un organisme modèle en génétique
  de Laurent Ségalat, Marie-Anne Félix, Michel Labouesse. Hermann (22 octobre 2002). Collection : Enseignement des sciences. Format : Broché - 200 pages. ISBN : 2705664270
  References
  Kammenga JE, Phillips PC, De Bono M, Doroszuk A. Beyond induced mutants: using worms to study natural variation in genetic pathways. Trends Genet. 2008 Apr;24(4):178-85. PMID: #18325626#
  Large EE, Mathies LD. Chromatin regulation and sex (...)

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