B. Cellular pathology

• caveolae
  9 June 2003

  Caveolae are small plasmalemmal vesicles of distinct, flask-shaped morphology. Caveolae are formed through the oligomerization of its structural proteins, caveolin-1 and caveolin-2, to form distinctive coat appearing as bipolar-oriented, thin striations surrounding the bulb of the caveloa.
  Membrane microdomains such as caveolae are sites of signal transduction. Many cell types including fibroblasts and endothelial cells contain small flask shaped invaginations of the plasma membrane. These (...)

• plasmalogens
  9 June 2003

  Definition: A plasmalogen is an ether lipid where the first position of glycerol binds a vinyl residue (from a vinyl alcohol) with the double bond next to the ether bond. The second carbon has a typical ester-linked fatty acid, and the third carbon usually has a phospholipid head group like choline or ethanolamine.
  In many tissues plasmalogens are minor constituents, but in heart tissue nearly 50% of phosphatidylcholine contains the alkenyl ether at carbon 1. Nervous tissues, testes and (...)

• plasmalogens biosynthesis
  9 June 2003

  Pathology:
  anomalies of plasmalogens biosynthesis (plasmalogens deficeincy)

• ether lipids
  9 June 2003
• peroxisomes
  9 June 2003

  peroxysomes, peroxysome

• ether lipids biosynthesis
  9 June 2003

  Exclusively localized to peroxisomes

• lipid biosyntesis
  9 June 2003

  lipid anabolism

• cytoplasmic membrane
  9 June 2003

  plasma membrane, plasmic membrane, cell membrane

• membrane trafficking
  9 June 2003

  membrane traffic, intracellular membrane trafficking, membrane transport

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