B. Cellular pathology

• telomere shortening
  19 July 2003

  telomere erosion, short telomeres

• telomeres
  19 July 2003

  Adj. telomeric

• cellular senescence
  19 July 2003

  cellular ageing

• intercellular junctions
  14 July 2003

  cell junctions, cellular junctions

• animatics in cells
  13 July 2003

  caveolar formation
  vesicular traficking

• transcytosis
  13 July 2003

  Function
  The apical and basolateral borders of epithelial cells are distinguished by their different protein and lipid components. The sorting of newly synthesized membrane constituents to the appropriate region of the cell is accomplished either in the trans-Golgi network or by transcytosis, the selected transport of proteins to the appropriate surface.
  Transcytosis is involved in the internalization of proteins and ligands at one surface and their transport to another.
  See also (...)

• desmosomes
  13 July 2003

  Definition: Specialized cell junctions that are formed by desmosomal cadherins and additional associated proteins into which intermediate filaments are inserted. Also known as macula adherens junctions or spot desmosomes.
  Desmosomes are essential adhesion structures in most epithelia that link the intermediate filament network of one cell to its neighbor, thereby forming a strong bond.
  Desmosomes are the most common type of intercellular junction in vertebrate epithelial cells. They are (...)

• vesicle trafficking
  13 July 2003

  vesicular transport of proteins, vesicular trafficking, intra-cellular-membrane transport

• secretion vesicles
  13 July 2003

  secretory granules

• cell polarity
  13 July 2003

  See also:
  epithelial polarity
  References
  Wodarz A. Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts. Curr Opin Cell Biol. 2005 Oct;17(5):475-81. PMID: #16099639#
  Suzuki A, Hirata M, Kamimura K, Maniwa R, Yamanaka T, Mizuno K, Kishikawa M, Hirose H, Amano Y, Izumi N, Miwa Y, Ohno S. aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity. Curr Biol. 2004 Aug 24;14(16):1425-35. PMID: #15324659# (...)

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