microRNA-155, miR-155
Home > A. Molecular pathology > miRNAs
miRNAs
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MIRN155
24 October 2007 -
MIRN125B2
29 August 2007hsa-mir-125b-2
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MIRN99A
29 August 2007hsa-mir-99a
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miRNA-let-7c
29 August 2007MIRNLET7C; let-7c
The let-7 miRNA was originally discovered in the nematode Caenorhabditis elegans, where it regulates cell proliferation and differentiation, but subsequent work has shown that both its sequence and its function are highly conserved in mammals.
Results have now linked decreased let-7 expression to increased tumorigenicity and poor patient prognosis.
Moreover, during normal development, accumulation of let-7 can be prevented by LIN28, a promoter of pluripotency. Based on (...) -
miRNAs
18 July 2004microRNA, microRNAs