Skin

• sclerosing perineurioma
  17 December 2003

  Cutaneous sclerozing perineurioma is a recently characterized, uncommon tumor composed of perineurial cells, which exhibits immunoreactivity for epithelial membrane antigen (EMA).
  Images
  https://twitter.com/DrLaurenStuart/status/700401453865832448
  Synopsis
  well-circumscribed masses
  thick collagen
  small, epithelioid cells exhibiting corded, trabecular and whorled growth patterns
  spindle cells with wavy nuclei end elongated cytoplasmic processes
  dense collagen stroma
  focal (...)

• cutaneous Rosai-Dorfman disease
  16 December 2003

  Rosai-Dorfman disease (RDD), previously known as sinus histiocytosis with massive lymphadenopathy, is a benign, idiopathic histiocytic proliferative disorder.
  Rosai-Dorfman Disease (RDD) is an idiopathic reactive proliferation of distinctive histiocytes that have abundant cytoplasm and commonly exhibit intracytoplasmic ingestion of inflammatory cells (emperipolesis).
  The histiocytes are immunopositive for S100 protein and are typically associated with an infiltrate of lymphocytes, plasma (...)

• generalized eruptive histiocytosis
  16 December 2003

  Definition : Generalized eruptive histiocytosis belongs to the cutaneous non-Langerhans cell histiocytoses and is a rare monocyte-macrophage proliferative disorder that usually follows a benign clinical course. It can be considered as a systemic multifocal juvenile xanthogranuloma.
  Synopsis
  erythematous macules and slightly elevated papules widely distributed over the trunk, neck, face, and thighs
  diffuse histiocytic infiltrate in the skin
  Ultrastructurally
  no Birbeck granules (...)

• cutaneous diffuse large B-cell lymphoma
  12 December 2003
• cutaneous lymphomas
  12 December 2003

  Digital cases
  JRC:10597 : cutaneous lymphoma (NOS).
  JRC:10600 : cutaneous lymphoma (NOS).
  JRC:10601 : cutaneous lymphoma (lymphocytic).
  JRC:10603 : cutaneous lymphoma (lymphocytic).
  UI:918 : Mycosis fungoides.
  JRC:10716 : Mycosis fungoides.
  Images
  cutaneous anaplastic large cell lymphoma - large atypical cells with mitosis, ALK negative.
  https://twitter.com/JJSpeiserMD/status/742413791825137665
  cutaneous peripheral T cell lymphoma (...)

• cutaneous bronchogenic cyst
  8 December 2003

  Synopsis
  polypoid mass
  multiple small cystic structures surrounded by the fibroadipose tissue
  lining epithelium: pseudostratified ciliated columnar epithelium with goblet cells or a single layer of ciliated or non-ciliated cuboidal to columnar cells
  The cystic walls contained a well-developed smooth muscle bundle, mucous glands and hyaline cartilage plate.
  Localization
  abdominal wall (#11844072#, #11732728#)
  References
  An unusual midline swelling—case report of a cutaneous (...)

• cutaneous ciliated cyst
  8 December 2003

  Synopsis
  cystic structure lined by stratified, ciliated, columnar epithelium
  Immunochemistry
  progesterone receptor + (#19479143#)
  epithelial membrane antigen + (#19479143#)
  carcinoembryonic antigen - (#19479143#)
  Localization
  abdominal wall (#11803285#)
  cheek (#11895515#)
  umbilicus (#16987293#)
  abdominal wall (#12357212#)
  inguinal area (#16556287#)
  perineum (#15370143#)
  leg (#19479143#)
  lower extremity
  References
  Cutaneous ciliated cyst on the leg in a woman of (...)

• keratinocytes
  3 December 2003

  WP
  A keratinocyte is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there. Those keratinocytes found in the basal layer (stratum basale) of the skin are sometimes referred to as "basal cells" or "basal keratinocytes".
  Pathology
  vacuolated keratinocytes
  dysplastic keratinocytes
  tumoral keratinocytes
  mitotic keratinocytes
  https://twitter.com/DrAldehyde/status/1295867333580410880
  See also
  epidermal basal cells (...)

• cutaneous development
  1 December 2003

  skin development

• sun sensitivity
  25 November 2003

  References
  Rees JL. The Genetics of Sun Sensitivity in Humans. Am J Hum Genet. 2004 Sep 15 PMID: #15372380#
  Brash DE. Sunlight and the onset of skin cancer. Trends Genet. 1997 Oct;13(10):410-4. PMID: #9351343#

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