Skin

• anastomoting strands of basaloid cells
  8 November 2020

  Differential diagnosis
  acrosyringeal nevus
  clear cell acanthoma
  CBC : fibroepithelioma of Pinkus
  poroma
  porocarcinoma

• eccrine syringofibroadenomae
  8 November 2020

  eccrine syringofibroadenoma (of Mascaro), acrosyringeal adenomatosis
  Eccrine poromatosis
  Linear eccrine poroma
  Acrosyringeal nevus of Weedon and Lewis
  Nevus syringoadenomatosus papilliferum PO
  Definition : A rare benign eccrine proliferation with anastomosing cords in a fibrovascular stroma.
  Synopsis
  anastomoting strands of epithelial cells
  anastomosing reticulated cords and strands of basaloid monomorphous cuboidal cells extending from the basal layer of epidermis into (...)

• epidermolytic hyperkeratosis
  8 November 2020

  Definition : lesional pattern.
  congenital epidermolytic hyperkeratosis / bullous ichthyotic erythroderma Brocq
  annular epidermolytic ichthyosis
  ichthyosis bullosa Siemens
  epidermal nevi
  epidermolytic acanthoma/leukoplakia
  epidermolytic palmoplantar keratoses
  incidental finding
  See also
  epidermolytic lesions / epidermolysis
  hyperkeratosis

• hyaline cell–rich chondroid syringoma
  8 November 2020

  Definition : Hyaline cell–rich chondroid syringoma is a rare benign variant of chondroid syringoma composed of cells with eosinophilic hyaline cytoplasm and plasmacytoid features, the origin of which remains elusive.
  Although very few cases have been reported in literature, it is important to be aware of this entity so as to avoid misdiagnosis on histopathological examination.
  Differential diagnosis
  May demonstrate atypical cells raising concern for a variety of malignant
  neoplasms: (...)

• neutrophilic epidermotropism
  8 November 2020

  Etiology
  neutrophilic urticarial dermatosis
  See also
  neutrophilic infiltrate

• dysplastic nevus
  8 November 2020

  Images
  https://twitter.com/MELanocyteMD/status/1324339579227459585
  Synopsis
  club-shaped rete / bridging rete
  shouldering of junctional component
  host response
  lamellar fibroplasia
  grading cytologic atypia: 2 vs. 3 tier classification system
  grading architectural disorder: woman shrugging
  See also
  melanocytic anomalies
  melanocytic tumors

• adnexal glandular tumors
  7 November 2020

  Types
  (a) apocrine differentiation: papillary hidradenoma (papillary fronds, vulvar / perianal) tubular apocrine adenoma (epidermal connection)
  (b) syringoma: small ducts with 2 rows of cells
  (c) papillary eccrine adenoma: cystic ducts and papillary fronds
  (d) papillated ducts open to epidermis: papillary syringadenoma (scalp) or nipple adenomatosis (nipple)
  (e) mixed tumor ( chondroid syringoma ): chondromyxoid stroma and tubular or anastomosing glands
  (f) sebaceous (...)

• squamoid adnexal tumors
  7 November 2020

  PO
  Types
  eosinophilic cells
  clear cells
  squamous cells with central keratinization
  (a) Solid lobules of eosinophilic cells : pilar sheath acanthoma (connected to crater-like cavity) acrospiroma (not connected to crater-like cavity)
  (b) Lobules with clear cells : acrospiroma (luminal differentiation) trichilemmoma (epidermal connection, peripheral palisading, thick basement membrane) sebaceous tumors
  (c) Lobules of squamous cells with central keratinization (...)

• basaloid adnexal tumors
  7 November 2020

  Types
  trichoepithelioma / trichoblastoma (ribbons of basaloid cells, cysts and fibroblastic stroma)
  trichofolliculoma (mature and immature hair follicles)
  cylindroma (jigsaw-puzzle appearance with thickened basement membrane)
  spiradenoma (basaloid cells with 2 cell types)
  sebaceous adenoma or sebaceous carcinoma
  eccrine poroma (large nodules connected to epidermis)
  eccrine acrospiroma (large dermal nodules)
  pilomatricoma (ghost cells)
  See also
  adnexal tumors diagnosis (...)

• keratoacanthoma-like squamous proliferation
  7 November 2020

  Etiology - Examples
  pembrolizumab

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