Single-cell technology

Links
https://www.diagenode.com/publications/view/3050

Links
https://www.diagenode.com/publications/view/3050

DNA mutation detection in single cell
Reference
Direct, genome-wide assessment of DNA mutations in single cells. Gundry M, Li W, Maqbool SB, Vijg J. Nucleic Acids Res. 2012 Mar;40(5):2032-40. doi:10.1093/nar/gkr949 . PMID: #22086961#

See also
single-cell technology
Open references
Single cell genomics of the brain: focus on neuronal diversity and neuropsychiatric diseases. Iourov IY, Vorsanova SG, Yurov YB. Curr Genomics. 2012 Sep;13(6):477-88. doi: 10.2174/138920212802510439 . PMID: #23449087# [Free]
Genome-wide copy number profiling of single cells in S-phase reveals DNA-replication domains. Van der Aa N, Cheng J, Mateiu L, Esteki MZ, Kumar P, Dimitriadou E, Vanneste E, Moreau Y, Vermeesch JR, Voet T. Nucleic (...)

In the postgenome era, biology and medicine are rapidly evolving towards quantitative and systems studies of complex biological systems.
Emerging breakthroughs in microfluidic technologies and innovative applications are transforming systems biology by offering new capabilities to address the challenges in many areas, such as single-cell genomics, gene regulation networks, and pathology.
See also
microfluidic technology
quantitative biomolecular analysis
systems biomolecular (...)

Links
singlecellgeneexpression.com
Fluidigm
References
Development and applications of single-cell transcriptome analysis. Tang F, Lao K, Surani MA. Nat Methods. 2011 Apr;8(4 Suppl):S6-11. Review. PMID: #21451510#

References
Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Jonathan M. Irish, Nikesh Kotecha & Garry P. Nolan. Nature Reviews Cancer 6, 146-155 (February 2006)

single cell technology