See also
Neuroblasts
neuroblastic tumors neuroblastomas ganglioneuroblastomas
Home > E. Pathology by systems > Nervous system
Nervous system
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tumoral neuroblasts
9 February 2006 -
neurogenesis
28 January 2006During the development of the mammalian central nervous system, neural stem cells and their derivative progenitor cells generate neurons by asymmetric and symmetric divisions. The proliferation versus differentiation of these cells and the type of division are closely linked to their epithelial characteristics, notably, their apical-basal polarity and cell-cycle length.
See also
development
neuroepithelial
radial glial cells
cell fate
adult neurogenesis
References
Jagasia R, (...) -
SPG7-associated hereditary spastic paraplegia
27 January 2006Muscle biopsies from the autosomal recessive form of patients with hereditary spastic paraplegia revealed histochemical signs of a mitochondrial disorder, namely RRFs, COX-negative fibres and succinate dehydrogenase-positive hyperintense fibres.
Linkage and subsequent mutation analysis revealed large deletions in a gene dubbed paraplegin. Owing to the homology with a yeast mitochondrial ATPase with both proteolytic and chaperone-like activities, it has been suggested that this form of (...) -
spinal dysraphism
11 October 2005spinal NTDs, spinal neural tube defects
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hereditary neuralgic amyotrophy
5 October 2005Definition: Hereditary neuralgic amyotrophy (HNA) is an autosomal dominant form of recurrent focal neuropathy characterized clinically by acute, recurrent episodes of brachial plexus neuropathy with muscle weakness and atrophy preceded by severe pain in the affected arm. Hereditary neuralgic amyotrophy can be caused by mutations in the SEPT9 gene (604061).
Hereditary neuralgic amyotrophy (HNA) is an autosomal dominant recurrent neuropathy affecting the brachial plexus. HNA is triggered by (...) -
synaptogenesis
11 June 2005WKP
See also
synapse
References
Haydon PG, Drapeau P. From contact to connection: early events during synaptogenesis. Trends Neurosci. 1995 Apr;18(4):196-201. PMID: #7778191# -
neuronal microtubules
24 May 2005References
Baas PW, Qiang L. Neuronal microtubules: when the MAP is the roadblock. Trends Cell Biol. 2005 Apr;15(4):183-7. PMID: #15817373# -
axonal transport
18 February 2005intraneuronal transport, neuronal transport
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axonal guidance
26 January 2005axonal targeting
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neurometabolic diseases
18 January 2005neurometabolic disorders