Exosome

exosome in pancreas cancer
Open references
High Prevalence of Mutant KRAS in Circulating Exosome-derived DNA from Early Stage Pancreatic Cancer Patients. 2017. doi:10.1093/annonc/mdx004.

Exosomes are small membrane vesicles released by most cell types including tumor cells. The intercellular exchange of proteins and genetic material via exosomes is a potentially effective approach for cell-to-cell communication and it may perform multiple functions aiding to tumor survival and metastasis.
Exosome in cancer
5-fluorouracil (5-FU)
The exosome has been shown to be inhibited by the antimetabolite drug fluorouracil, which is a drug used in chemotherapy treatment of cancer. (...)

Definition: The exosome complex is a multi-protein complex, capable of degrading various types of RNAs. Exosomes are extracellular cell-derived phospholipid nanovesicles that function as signalosomes, transmitting prodigious amounts of bioactive molecules to specific recipient tissues.
Exosomes (versatile, cell-derived nanovesicles naturally endowed with exquisite target-homing specificity and the ability to surmount in vivo biological barriers) hold substantial promise for developing (...)